S (special place in my heart)

Mamagulin

Ceremonial Beast

Kaiser Crab

Insatiable

Soul Fysh

Queen

Vantom

Kin Priest

Test Subject C10

F (fuck you)

Knowledge Demon

Waterfall Giant

Doormaker

Created Mar 15, 2026

Create your own slay the spire 2 bosses rankings with this tier list. Place each item into S, A, B, C, or D tier, then share and see how your picks compare with the community.

By TierBuddy Community

S (special place in my heart) Tier

Mamagulin
Ceremonial Beast

A Tier

Kaiser Crab
Insatiable
Soul Fysh

B Tier

Queen

C Tier

Vantom
Kin Priest
Test Subject C10

F (fuck you) Tier

Knowledge Demon
Waterfall Giant
Doormaker