Create your ultimate tboi boss difficulty tier list and rank everything from S tier to D tier. This tboi boss difficulty ranking tool lets you compare, vote, and share your tier list with the community. Looking for the best tboi boss difficulty? Use this tier list to settle the debate and see how your tboi boss difficulty rankings stack up against other users on TierBuddy. Popular categories include gaming, pc-games, the-binding-of-isaac, indie-games.